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Our laboratory has focused on Porin B PorBan outer membrane protein from Neisseria meningitidis and TLR2 ligand-based adjuvant, to characterize specific molecular and cellular pathways involved in improved immune responses induced by vaccine adjuvants. Downstream from this stimulation, we have observed enhanced antigen uptake in antigen presenting cells APCgreater antigen deposition in secondary lymphoid organs, and promotion of germinal center reactions.


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